Volume : VII, Issue : VII, July - 2018

Clinical profile and outcomes of acute lymphoblastic leukaemia in children; an experience from a newly established pediatric oncology unit from eastern zone of India.

Saroj P Panda, Bhabagrahi Mallick, Mrutunjay Dash, Priyanka Samal, Sourav K Mishra, Soumya S Panda

Abstract :

Objective:One third of all childhood cancers are leukaemia; approximately 10,000 new cases are diagnosed in India each year. To describe the clinical characteristics and outcomes of paediatric acute lymphoblastic leukemia (ALL).  Material and Methods:  Medical records of pediatric ALL diagnosed between April 2015–March 2018 were reviewed using a custom data collection sheet. Results: Seventy one cases were enrolled;median age 4 years, 52% male.Common clinical findings at presentation were fever(77%), hepatosplenomegaly(70%), lymphadenopathy (37%) and pallor(30%). Ninety two percent patients achieved complete hematologic remission. Infection was the most common cause of mortality. Event–free survival and overall survival at 2 years were 67%and 79% respectively. Conclusion:  Clinical characteristics are similar to those reported in the literature. Cytogenetic study (conventional karyotyping and FISH analysis) needs to be monitored for a better result. Chemotherapy regimen used appears to be effective, tolerable and feasible.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Saroj P Panda, Bhabagrahi Mallick, Mrutunjay Dash, Priyanka Samal, Sourav K Mishra, Soumya S Panda, Clinical profile and outcomes of acute lymphoblastic leukaemia in children; an experience from a newly established pediatric oncology unit from eastern zone of India., INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-7 | July-2018


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