Volume : VI, Issue : VI, June - 2017

CLINICAL PROFILE OF 100 PATIENTS WITH PORTAL HYPERTENSION IN SIR T. GENERAL HOSPITAL, BHAVNAGAR

Dr. Rutul Dave, Dr. Pramod R Jha, Dr. Alpesh Vora, Dr. Nisha S Lalwani

Abstract :

 ·         Objective: To study clinical & investigative profile of patients with portal hypertension. To discuss etio–pathogenesis of portal hypertension. To study the predictive power of non–invasive investigative parameters (clinical, biochemical, radiological) for detection of esophageal varices in patients with portal hypertension (PHT) as compared to invasive parameters (upper gastrointestinal endoscopy). To study outcome in patients of portal hypertension. ·         Materials and methods: 100 patients with PHT, from April 2015 to March 2016, were studied. Those who had age <12 years & not giving consent were excluded. Detailed clinical history was taken and physical examination was done. Patients underwent the required hematological, biochemical, radiological and endoscopic investigations. ·         Results: Alcoholic liver disease is most common cause of portal hypertension with middle aged males being most commonly affected population. Hepatic encephalopathy & hepatorenal syndrome are major causes of mortality in patients with portal hypertension, whereas esophageal varices & ascites are most common specific presenting complications causing large number of morbidity. Platelet count/spleen size ratio showed a significant correlation between presence or absence and grade of esophageal varices (p < 0.00015). If a cut–off value of 1,000 is taken, then 85% patients with esophageal varices have ratio <1,000 while 26% of patients with ratio <1,000 did not have any varices. It was also observed that lower the ratio, higher the grade of varices.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Rutul Dave, Dr. Pramod R Jha, Dr. Alpesh Vora, Dr. Nisha S Lalwani, CLINICAL PROFILE OF 100 PATIENTS WITH PORTAL HYPERTENSION IN SIR T. GENERAL HOSPITAL, BHAVNAGAR, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-6 | JUNE-2017

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