Clinical Profile of cirrhosis of liver  study carried out in a Tertiary Care Centre

Dr Aher Sangeeta; Dr Gaikwad Sushma; Dr.Ashok Kumar

Volume : VI, Issue : IV, April - 2017

Clinical Profile of cirrhosis of liver study carried out in a Tertiary Care Centre

Dr Aher Sangeeta, Dr Gaikwad Sushma, Dr. Ashok Kumar

Abstract :

Background: Cirrhosis is an increasing cause of morbidity and mortality in the developed countries. The main causes in developed countries are infection with hepatitis C virus, hepatitis B virus, chronic alcoholism, non–alcoholic liver disease(3). The prevalence of cirrhosis is difficult to assess and probably higher than reported because the initial stages are asymptomatic so the disorder is undiagnosed. Alcohol related cirrhosis is increasing therefore, we aimed to study cirrhosis of liver with reference to its, aetiology, clinical presentation, complications, prognostic features and mortality(4).

Materials and methods: 50 adult patients of both sexes, diagnosed as cirrhosis of liver disease and willing to give written informed consent were included in this study. Statistics: The data was presented as mean � standard deviation (mean � SD). The results obtained from the scales were compared using appropriate parametric (Student �t�test, ANOVA) and non parametric tests (Chi–Square, Mann Whitney U, Wilcoxon Sign Rank test) wherever applicable. p <0.05 was considered statistically significant.

Results: In our study, out of 50 patients, 48 (96%) were males & 2 (4%) were females. Therefore maximum number of patients were in the age group of 31–50 yrs. Aetiology were alcohol related (72.2%), HBV (8.9%), HCV (3.2%), Autoimmune Hepatitis (0.9%), and NASH (1%). Complications were ascites (78.6%), variceal bleeding (43.4%), hepatic encephalopathy (21.6%), Spontaneous bacterial peritonitis 4.2%, Hepatorenal syndrome (2.7%).50% had Child C disease, 83% had MELD between 10–29. Mortality was 7.8% and highest among alcoholic cirrhosis (6.8%). So, incidence of cirrhosis in Alcoholic liver disease=56.66% Incidence of fatty liver disease in Alcoholic liver disease =30%.