IJSR - International Journal of Scientific Research

Dr. Amruta Kamble; Dr. Shekhar N Pradhan; Dr. Rajesh P Singh; Dr. Mukhi Jayesh

Volume : V, Issue : VIII, August - 2016

Clinical Profile of Nail Changes in Systemic Diseases

Dr. Amruta Kamble, Dr. Shekhar N Pradhan, Dr. Rajesh P Singh, Dr. Mukhi Jayesh

Abstract :

 Background: Nail changes occur in a wide variety of systemic diseases which requires careful examination of fingernails and toenails. Aims and Objectives: The present study was conducted to evaluate the frequency of various nail changes, in patients who have nail involvement with systemic diseases and to assess the specificity of nail changes with disease status. Materials and Methods: Patients 360 in number were selected randomly in whom nail changes were associated with systemic diseases attending Dermatology opd and inpatients of other departments. Patients in whom nail changes were associated with trauma, primary muco–cutaneous disease were excluded. Results: Maximum patients were in the age group of 31–50 years accounted for 63%. Most frequent nail involvement was clubbing found in 40.8% patients, followed by pallor 32.5%, Beau’s lines 11.4 %, and platynychia 8.9 %. Most frequent system associated with nail changes was respiratory system which included 41.1% patients, followed by hematopoietic system 13.9%, renal 13.3%, GIT 12.5%, endocrine 4.4% and cardiovascular system 2.8%. Conclusion: Nail changes were most commonly seen in patients with systemic illness more than 6 months. Diabetes or hypertension was found in 28.3% patients. Most frequent nail involvement was clubbing followed by pallor, Beau’s lines. Most frequent system associated with nail changes was respiratory system, hematopoietic system, renal, GIT and liver. Clubbing was mostly seen in patients having pulmonary Koch‘s. Terry‘ nail was found relatively specific in the patients of liver cirrhosis. HHN (half and half nails) confirms the diagnosis of chronic renal failure.