Volume : V, Issue : VIII, August - 2016

CLINICOPATHOLOGICAL CORRELATION OF ACQUIRED HYPOPIGMENTARY DISORDERS

Dr Jasmine Chug, Dr Kuldip Singh Chahal

Abstract :

 Hypopigmentation means decrease of melanin in skin which appears white or lighter than normal colour. The hypopimented disorders can be genetic or acquired. Acquired hypopigmentary disorders include various inflammatory, infectious disorders. The aim of this study was to study histopathological findings in various acquired hypopigmented disorders using routine Haematoxylin and Eosin stain and to study correlation of clinical and histopathological findings of various acquired hypopigmented disorders. The present study was conducted for a period of three years. Skin biopsy from 50 patients which included the lesion and the perilesional adjacent normal looking area, were received in the Department of Pathology, Government Medical College, Amritsar.Then paraffin embedded tissue sections were stained with routine haemtoxylin and eosin and diagnosis was made on the basis of the histopathological findings. Maximum numbers of patients had presented with clinical diagnosis of vitiligo (20 cases) followed by leprosy (BT–10 cases and LL–5 cases). On histopathology 24 were typified as vitiligo,11 as leprosy (11 PB leprosy and 5 MB leprosy),6 out of 50 cases were diagnosed on histopathology as lichen sclerosis et atrophicus, 1 as morphea, pityriasis versicolor, post inflammatory dermatitis and idiopathic guttate hypomelanosis each. The overall level of concordance between clinical and histopathological diagnosis was noted in 80% cases. Adequate clinical data and workup in combination with pathological resources can help in elucidation of specific etiology and good clinicopathological correlation.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Jasmine Chug, Dr Kuldip Singh Chahal CLINICOPATHOLOGICAL CORRELATION OF ACQUIRED HYPOPIGMENTARY DISORDERS International Journal of Scientific Research,Volume : 5 | Issue : 8 |August 2016


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