CO-RELATION BETWEEN CARDIOVASCULAR RISK FACTORS AND CAROTID ARTERY INTIMAL-MEDIAL THICKNESS IN PATIENTS ON MAINTENANCE HEMODIALYSIS

Dr. Mohammad Jabed; Dr. Alok Kumar; Dr Dorchhom Khrime; Dr. V.K Sharma; Dr Shantanu Aggarwal

Volume : IX, Issue : V, May - 2020

CO-RELATION BETWEEN CARDIOVASCULAR RISK FACTORS AND CAROTID ARTERY INTIMAL-MEDIAL THICKNESS IN PATIENTS ON MAINTENANCE HEMODIALYSIS

Dr. Mohammad Jabed, Dr. Alok Kumar, Dr Dorchhom Khrime, Dr. V. K Sharma, Dr Shantanu Aggarwal

Abstract :

Background: Cardiovascular Diseases have been recognized for many years to be major cause of morbidity and mortality in patient on renal replacement therapy. CIMT is well–established index of systemic atherosclerosis that co–relate well with the incidence of coronary heart disease and stroke. The aim of this study is to look association of serum phosphate, serum PTH and other cardiac risk factors with carotid intimal thickness in patients on MHD Methods: Study population comprised of 00 patients of CKD on maintenance hemodialysis. Their basic demographic data was recorded. Patients were evaluated for serum lipid profile, CIMT, Serum PTH and serum phosphate. All patients underwent relevant clinical examination by doctor in unit. We applied appropriate statistics to analyze data. Results There were 100 patients of CKD on hemodialysis. Study cohort comprised of 69% males and 31% females. Mean age of the patients was 56.98�12.93 years. Mean serum phosphate level was 5.13�1.9 mg%. A positive correlation was seen between serum phosphate levels and serum PTH with carotid intimal medial thickness in right carotid artery. There was a negative correlation between CIMT and Hb of CKD patients which was statistically significant. There was a positive correlation of CIMT with total cholesterol and it was found statistically significant. CONCLUSION Total serum cholesterol showed significantly positive correlation with CIMT and Hemoglobin had negative correlation with CIMT.