Volume : VIII, Issue : IX, September - 2019

Cognitive derangement in Smokeless tobacco Users.

Dr Ashish Raj, Dr Anupama Gupta, Dr Rajesh Gupta, Raghav Gupta

Abstract :

Background: Tobacco use is a public health concern worldwide. Nicotine (highly addictive psychoactive drug), which is a main constituent of smokeless tobacco exerts multiple local and systemic effects. Chronic exposure from SLT has also been reported to cause neuro–muscular disease. Tobacco chewing may cause cognitive decline. It is associated with deficiency in executive function, cognitive flexibility, intellectual abilities learning and memory processing. However we don’t have much literature available, so we planned to assess cognitive function in SLT users using MoCA test. Objective: To assess cognitive function MoCA (Monteral Cognitive Assessment) tests in chronic tobacco chewers and to see its effect by increasing number of pouch year on cognition. Method: The study was conducted in Department of Physiology, PGIMS, Rohtak. A total of 80 subjects in the age group of 25–50 years were included, and divided into two groups. Group I included 40 chronic tobacco chewers with history of minimum 2 pack years and group II were controls who didn’t use tobacco in any form. Subjects with a history of any drug abuse, alcoholism, diabetes, hypertension, COPD or any neurological disease were excluded from the study. Further tobacco chewers were subdivided into 3 groups A, B and C based on pouch year. The tobacco chewers and the controls were subjected to MoCA test. Results: The mean age of chewer was 31.52±6.5 years and control 30.5±4.9 years. The mean MoCA score was significantly decreased (p<0.05) in SLT users. Group C (tobacco chewer 10–15 pouch year) shows positive correlation with Group B and Group A indicating decrease in cognitive function with increasing number of pouch year. Conclusion: Smokeless tobacco has deleterious effect on cognition. The deleterious effect on cognition increases with increasing number of pouch years in tobacco chewers.

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

COGNITIVE DERANGEMENT IN SMOKELESS TOBACCO USERS., Dr Ashish Raj, Dr Anupama Gupta, Dr Rajesh Gupta, Raghav Gupta INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-9 | September-2019

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