Comparative clinical study of magnesium sulphate and fentanyl as adjuvant to intrathecal bupivacaine in patients with pregnancy induced hypertension undergoing caesarean section

Ajeet Jyotipurkar; Rajni Thakur

Volume : VIII, Issue : II, February - 2019

Comparative clinical study of magnesium sulphate and fentanyl as adjuvant to intrathecal bupivacaine in patients with pregnancy induced hypertension undergoing caesarean section

Ajeet Jyotipurkar, Rajni Thakur

Abstract :

Introduction: To study effect of magnesium sulphate and fentanyl as adjuvant to intrathecal bupivacaine (0.5% ) in patients with pregnancy induced hypertension undergoing caesarean section.

Method: 64 pregnant patients with pregnancy induced hypertension undergoing caesarean section divided into group MB (magnesium sulphate ) and FB (fentanyl) with 0.5 % bupivacaine for spinal anaesthesia and patients outcome were studied.

Result : There were no significant differences in patient demographics, surgery time , perioperative hemodynamic parameters and APGAR score in both groups. The onset and mean duration of motor block was found prolonged with magnesium compared to fentanyl group. Side effects were seen more in FB compared to group MB.

Conclusion: Addition of magnesium sulphate to intrathecal bupivacaine delays the onset of motor blockade but prolongs the duration of analgesia and reduces postoperative analgesic requirements without much side effects and any adverse effect on APGAR score