Volume : VIII, Issue : V, May - 2019

Comparative Study Of Histopathology In Correlation With Estrogen Receptor And Progesterone Receptor In Case Of Fibroadenoma

Dr Shahaji Chavan, Dr Rahul Banik, Dr Mahindra Bendre, Dr Srujan Kondreddy, Dr Karan Jaiswal, Dr Vemuri Nandan, Dr R. Venkata Lakshmi Manasa

Abstract :

INTRODUCTION: Fioadenomas are the most common east masses in adolescents. They may present a challenge for physicians as treatment guidelines are lacking in this population. Types of fioadenoma include juvenile, cellular, or giant. Differentiation must be made between giant fioadenoma and juvenile hypertrophy. Patients who present with east masses should undergo a detailed evaluation to assess the mass, including an ultrasound. Surgical excision of fioadenoma may be performed if the mass is symptomatic and/or rapidly growing. Hence the present study was done at our tertiary care centre to study the correlation, occurrence and recurrence of fioadenoma with ER and PR status. RESULTS: The mean age of the patients was 35.28 ± 10.25 years. 4 (8%) patients started menstruation at age of 12 years while 19 (38%) patients started menstruation at 13 years of age. 21 (42%) and 6 (12%) patients started menstruation at 15 and 16 years of age respectively. There was no significant association between Estrogen Receptor (ER) status and age, menopausal history, laterality and gross size of tumour of patients (p>0.05). Progesterone Receptor (PR) status and its intensity was seen to correlate with tumor size (p<0.05). On the other hand no significant association was noted between PR status and age, menopausal history, laterality and gross size of tumour of patients (p>0.05). CONCLUSION: Immunohistochemical diagnosis for estrogen and progesterone receptors has proved to be advantageous and an aid in the diagnosis. Several cases of diagnostic dilemma such as invasion or pseudoinvasion, ductal or lobular type, and in situ or invasion can be reliably diagnosed by the use of immunohistochemical diagnosis of estrogen and progesterone receptors.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

COMPARATIVE STUDY OF HISTOPATHOLOGY IN CORRELATION WITH ESTROGEN RECEPTOR AND PROGESTERONE RECEPTOR IN CASE OF FIBROADENOMA, Dr Shahaji Chavan, Dr Rahul Banik, Dr Mahindra Bendre, Dr Srujan Kondreddy, Dr Karan Jaiswal, Dr Vemuri Nandan, Dr R. Venkata Lakshmi Manasa INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-5 | May-2019

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