Comparative Study of Rapid Malaria  Antigen Test with Giemsa Stained  Peripheral Smear for Diagnosis of Malaria

Suchita J Lakhani; Krunal K Shah; Pragnesh P Patel

Volume : II, Issue : VI, June - 2013

Comparative Study of Rapid Malaria Antigen Test with Giemsa Stained Peripheral Smear for Diagnosis of Malaria

Suchita J Lakhani , Krunal K Shah, Pragnesh P Patel

Abstract :

Malaria is thought to kill between 1.5 to 2.7 million people worldwide each year. The most common test for malaria diagnosis remains the microscopic examination of giemsa or the fields - stained blood smears. The serological test is based on the detection of Plasmodium falciparum specific histidine rich protein II (HRP II) and a pan malarial species specific LDH. Method: This study included 220 patients. For each sample thin and thick smear blood films were made and examined for malaria parasite by light microscopy and also by Accucare test. Results: The blood films results indicated that 21 (9.5%) patients were infected with malaria and the rest 199 (90.5%) were malaria negative. Among positive patients Plasmodium vivax was detected in 5 cases (23.8%) and Plasmodium falciparum in 10 cases (47.6%) and 6 cases mixed infection (28.6%) correspondingly, the ACCUCARE test results indicated that 20 (9.1%) of the patient sample were positive for malaria parasites and 200 (90.9%) were malaria negative.Out of 20 patients cases, infection with Plasmodium vivax accounted for 5 (25%) while infection with Plasmodium falciparum accounted for 9 (45%) and 6 (30%) with mixed infection.