Volume : IX, Issue : I, January - 2020

Comparison of continuous infusion of vecuronium and atracurium in laparotomies at SMCH, Ghaziabad, U.P.

Dr. Deepak Mehrotra, Dr. Nitin, Dr. Debarshi Jana

Abstract :

Sixty adult patients of either sex, 25 – 45 years of age, belonging to ASA physical status I or II, who were scheduled for midline and paramedian laparotomies under general anaesthesia lasting for up to two hours were recruited for a prospective randomized controlled study intended to compare vecuronium and atracurium when the drugs were used as a continuous infusion. The drugs were compared with respect to recovery from neuromuscular blockade on stopping the infusion and cardiovascular performance. The study was approved by the Institutional Ethics Committee and all patients enrolled provided written informed consent. Patients were randomly allocated into two equal groups and received either vecuronium (Group I) or atracurium (Group II) in intravenous infusion for maintenance of muscle relaxation. Fentanyl was used as analgesic and inductions were done with thiopental and intubation with vecuronium (0.1 mg/kg body weight) in Group I patients and atracurium (0.5 mg/kg body weight) in Group II patients. Anesthesia was maintained with 33% oxygen in nitrous oxide and incremental doses of fentanyl and propofol infusion at a rate of 2–4 mg /kg/hour. Intravenous infusions of muscle relaxants were adjusted to maintain 90% of neuromuscular blockade monitored by stimulating ulnar nerve at the wrist by a peripheral nerve stimulator throughout surgery. At the end of the procedure, at 25% recovery of twitch height, neuromuscular blockade was reversed with neostigmine and glycopyrrolate.

Keywords :

Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

COMPARISON OF CONTINUOUS INFUSION OF VECURONIUM AND ATRACURIUM IN LAPAROTOMIES AT SMCH, GHAZIABAD, U.P., Dr. Deepak Mehrotra, Dr. Nitin, Dr. Debarshi Jana INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-1 | January-2020

Number of Downloads : 200

References :