Volume : III, Issue : IX, September - 2014
Comparison of Efficacy and Safety of Iron Sucrose in Patients with Anemia in Pregnancy and Chronic Kidney Disease with Historical Control Groups of Different Parenteral Iron Preparations
Dr. Panchal Pavan J. , Dr. Desai Mira K.
Abstract :
Objective: Comparison of efficacy and safety of iron sucrose in patients with anemia in pregnancy and chronic kidney disease with historical control groups of different parenteral iron preparations Methods: An observational, prospective, historical controlled study in patients of anemia in pregnancy and chronic kidney disease (CKD) receiving iron sucrose were included. Demographic details, clinical history, baseline hemoglobin, anemia indices data were recorded in a case record form. The patients were followed up monthly for 12 weeks and observed for clinical and hematological improvement and adverse drug reactions (ADRs). Improvement in laboratory parameters with iron sucrose treated patients were compared with historical control groups of different iron preparations. The data was analyzed using paired t–test, unpaired t–test and Fisher`s exact test. Results: Out of total 84 iron sucrose treated patients, 47 were pregnant and 37 were CKD patients. One historical control group includes iron dextran treated 78 CKD patients and second group was of 30 anemic pregnant patients treated with iron sorbitol citric acid. Iron sucrose, iron dextran and iron sorbitol citrate significantly (P
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DOI : 10.36106/ijsr
Cite This Article:
Dr. Panchal Pavan J., Dr. Desai Mira K. Comparison of Efficacy and Safety of Iron Sucrose in Patients with Anemia in Pregnancy and Chronic
Kidney Disease with Historical Control Groups of Different Parenteral Iron Preparations International Journal of Scientific Research, Vol : 3, Issue : 9 September 2014
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Dr. Panchal Pavan J., Dr. Desai Mira K. Comparison of Efficacy and Safety of Iron Sucrose in Patients with Anemia in Pregnancy and Chronic Kidney Disease with Historical Control Groups of Different Parenteral Iron Preparations International Journal of Scientific Research, Vol : 3, Issue : 9 September 2014
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