Comparison of Intrathecal Bupivacaine and LevoBupivacaine in patients undergoing perineal and lower limb surgeries.

Anis–ur–Rehman; Waqar–ul–Nisa; Sheikh Irshad; Ayaz Farooqi; Wasim Ahmad

Volume : VI, Issue : V, May - 2017

Comparison of Intrathecal Bupivacaine and LevoBupivacaine in patients undergoing perineal and lower limb surgeries.

Anis Ur Rehman, Waqar Ul Nisa, Sheikh Irshad, Ayaz Farooqi, Wasim Ahmad

Abstract :

The dangers of long acting local anaesthetic Bupivacaine widely used for spinal anaesthesia if inadvertently gaining vascular access,led us to compare a reportedly less toxic agent Levo–bupivacaine with Bupivacaine for spinal anaesthesia in patients undergoing perineal and lower limb surgeries. 100 patients of either sex with physical status ASA grade I and II, aged 25 to 60 years, scheduled for perineal and lower limb surgeries under spinal anaesthesia were included in the study. Patients were randomly divided into two equal groups of 50 each.Patients were randomized to receive 3 ml of hyperbaric bupivacaine or levobupivacaine. The onset and duration of sensory block, onset and duration of motor block and duration of analgesia were recorded. The median highest level in both these groups was T6. The difference observed was statistically insignificant (p–value >0.05). The mean of onset of highest sensory block in bupivacaine group was 11.60 minutes & and that in the levobupivacaine group was 12.54 minutes. The difference observed was statistically insignificant (p–value >0.05). The mean time to achieve grade III motor block in bupivacaine group was 6.80 min. and that in the levobupivacaine group was 7.30 min. The difference observed was statistically insignificant (p–value >0.05).This study indicates that 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric bupivacaine have equally effective potencies for spinal anaesthesia, both regards to onset of sensory and motor block, total duration of sensory and motor block and sensory regression to S2,however levobupivacaine has the added advantage of less toxic effects if accidently gone intravascular with a similar duration of sensory block as that of bupivacaine.