COMPARISON OF ONDANSETRON AND PALANOSETRON FOR ATTENUATION OF SPINAL INDUCED HYPOTENSION .

Pramod K Palai; Hari Krishna Dalai; Swagata Biswas

Volume : VI, Issue : III, March - 2017

COMPARISON OF ONDANSETRON AND PALANOSETRON FOR ATTENUATION OF SPINAL INDUCED HYPOTENSION .

Pramod K Palai, Hari Krishna Dalai, Swagata Biswas

Abstract :

150 patients scheduled for elective abdominal hysterectomy,were randomly divided into three groups. 10mins before spinal anaesthesia, Group �O� wasgiven 4mg ONDANSETRON ,group �P� received PALANOSETRON 75 microgram , group �S� received normal saline; over 5mins. Mean arterial blood pressure, heart rate, nausea, shivering, adycardia and requirement of vasopressor were assessed. The fall inmean arterial pressure was least in �O� group, followed by �P� group and �S� group. Nosignificant difference was observed regarding heart rate. Group �O� & �P� had significantly lower requirement of vasopressor .