COMPARISON OF PROTEIN/CREATININE RATIO IN SINGLE VOIDED URINE SAMPLE WITH 24 HOURS URINE PROTEIN FOR ESTIMATION OF PROTEINURIA IN PREGNANCY INDUCED HYPERTENSION

Dr.Shabinakhan; Dr.Shobhamukherjee; Dr. H.K. Premi; Dr.Shikha Dhawan; Dr. Shreya Singh

Volume : IV, Issue : IX, September - 2015

COMPARISON OF PROTEIN/CREATININE RATIO IN SINGLE VOIDED URINE SAMPLE WITH 24 HOURS URINE PROTEIN FOR ESTIMATION OF PROTEINURIA IN PREGNANCY INDUCED HYPERTENSION

Dr. Shabinakhan, Dr. Shobhamukherjee, Dr. H. K. Premi, Dr. Shikha Dhawan, Dr. Shreya Singh

Abstract :

Objectives: To compare protein/creatinine ratio (P:C) a in single voided urine sample with 24 hours urine protein for estimation of proteinuria in pregnancy induced hypertension (PIH). Methods: A total of 50 pregnant women with pre eclampsia and gestational hypertension attending the teaching hospital attached to RMCH,Bareilly, was selected with following inclusion and exclusion criteria. Inclusion Criteria. Pregnant women with, pre eclampsia and gestational hypertension of blood pressure 140/90 mmHg or more recorded on two occasions at least 6 hours apart or single diastolic reading of >= 110 mmHg and the presence of proteinuria of > trace as detected by a qualitative test done on a random sample of urine. Exclusion Criteria Pre existing renal disease – A stable renal function was ascertained by doing a blood urea and serum creatinine. Urine analysis was done for all the patients to exclude the presence of microscopic haematuria, casts and bacteuria Results: There was a significant correlation between 24 hours urine protein and P:C ratio. These also showed statistically significant linear relationship. Conclusion: The spot urinary protein/creatinine ratio appears to be an excellent alternative to 24 hours urine protein. A level above 0.2 is a good indicator of significant proteinuria.