Volume : II, Issue : XII, December - 2013

Comparison of Vitamin C Status in Type 2 Diabetic Patients and Normal Controls

Shailaza Shrestha, Rahul Rai

Abstract :

Our aim was to evaluate the levels of vitamin C, an antioxidant, as a marker of oxidative stress in type 2 diabetes and to correlate them with glycemic control. Antioxidant status in terms of vitamin C was estimated in 30 controls and 30 type 2 diabetic mellitus (DM) patients. Analysis was done using student’s‘t’ test for comparison between two groups and One Way ANOVA (F-test) for multiple group comparison. FBS, PPBS and HbA1c levels of diabetic patients were significantly higher (p<0.001), whereas vitamin C levels were significantly lower relative to their controls (p<0.001). Vitamin C showed statistically signifcant decrease with glycemic control and it was also negatively correlated with HbA1c (r = -0.47, p<0.008). Type 2 DM is associated with OS causing depletion in antioxidant levels. As it might lead to diabetic complications, antioxidants can be supplemented as a therapeutic measure to type 2 DM patients.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Shailaza Shrestha, Rahul Rai Comparison of Vitamin C Status in Type 2 Diabetic Patients and Normal Controls International Journal of Scientific Research, Vol.II, Issue.XII December 2013

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