IJSR - International Journal of Scientific Research

SATYA SHUBHANGI; AARTI VERMA; PANKAJ KUMAR DAS; V N SINGH

Volume : VII, Issue : IV, April - 2018

CONTRACEPTIVE EFFECT OF MOMORDICA CHARANTIA SEEDS ON SEMINAL PROFILE OF MICE

Satya Shubhangi, Aarti Verma, Pankaj Kumar Das, V N Singh

Abstract :

The objective of this research is to study the impact of aqueous extract of Momordica charantia seeds on seminal profile of male mice. The effect of Momordicacharantia seeds causes significant decline in sperm count,motility of spermatozoa and pH of semen while there is an increase in mortality of sperms of Swiss Albino male mice. The aqueous extract of Momordicacharantia seeds was orally administrated 0.5 ml(250 mg/kg/bw/day) to male mice for 10, 20, 30, 40, 50 daysalong with control group of mice. The research investigation was carried out on seminal quality of mice on above parameters. The extract of Momordicacharantia seeds causes significantly decline during 10 days (P‹0.1), 20 days (P‹0.01), 30 days (P‹0.01), 40 days (P‹0.001) and 50 days (P‹0.001) treatment in sperm count, sperm motility and seminal pH with the respect to control group of mice while there is an significantly increase in mortality of spermatozoaduring 10 days (P‹0.1), 20 days (P‹0.01), 30 days (P‹0.01), 40 days (P‹0.001) and 50 days exposure than control (P‹0.001). The alteration occurred in seminal quality of male mice signifies that aqueous extract of Momordicacharantia seeds alters the seminal parameters and thus causes contraceptive effect in treated group of mice than control.