Correlation between Hypertension and Diabetes with Serum Lipid Disturbances in Indian Population

Deepesh Agarwal; Ramanand P Sinha

Volume : VII, Issue : XI, November - 2018

Correlation between Hypertension and Diabetes with Serum Lipid Disturbances in Indian Population

Deepesh Agarwal, Ramanand P Sinha

Abstract :

Background: Dyslipidaemia has been considered as the significant cause of mortality and morbidity in cardiovascular diseases. In the present study we sought to determine the connection of lipid disturbances in diabetic and hypertensive patients compared against non–diabetic and normotensive control patients.

Methods: A total of 310 patients were included in this retrospective, single–centre study conducted between Feuary 2013 and January 2014. The patients were divided in two groups; case group, those who were suffering from comorbid diabetes and hypertension and control group, those who neither suffered from diabetes nor hypertension. Patients were evaluated diabetes and hypertension along with basic demography and lipid profile.

Results: Of total 310 patients, 164 patients diagnosed with diabetes and hypertension both (case group), and a control group of 146 patients who neither suffered from diabetes nor hypertension. Significant differences were observed in triglycerides (TG) (p value <0.001; CI = 1.53–3.88), high density lipoprotein (HDL) in males (p value <0.05; CI = 1.11–3.69), TG/non–HDL cholesterol (p value <0.05; CI = 1.12–2.75) and TG/HDL lipid parameters (p value <0.01; CI = 1.29–3.23).

Conclusion: The present study demonstrates that patients with hypertension and diabetes have disturbed lipid profile than the patients without hypertension and diabetes. Hypertensive and diabetic patients should be evaluated for lipid profile at regular intervals for better management and prevention of CVD.