Correlation of Common Lipid Profile and Carotid Artery Intima Media Thickness in Patients of Ischemic Stroke

Dr Ramesh Patel; Dr. DP Singh

Volume : VII, Issue : IX, September - 2018

Correlation of Common Lipid Profile and Carotid Artery Intima Media Thickness in Patients of Ischemic Stroke

Dr Ramesh Patel, Dr. Dp Singh

Abstract :

Aim: The present study was postulated to correlate common lipid profile and carotid artery intima media thickness (cIMT) in patients of ischemic stroke.

Materials and Methods:This was a single–centred, case–control study which included a total of 100 patients, from which 50 patients were of ischemic stroke (cases) and 50 patients without ischemic stroke (controls). The cIMT of each subject was measured at 8 sites in the carotid artery both sides using Doppler carotid imaging and mean cIMT was measured. Total lipid profile, cardiovascular and common baseline investigation were performed for each patient.

Results:Mean cIMT in subjects with stroke and in subjects without stroke was found to have statistically significant difference (0.913 � 0.120 mmvs. 0.732 � 0.119 mm, p< 0.0001, respectively). Total serum cholesterol, serum triglycerides and LDL level demonstrated positive correlation with the cIMT and HDL level was found to be negatively correlated with cIMT.

Conclusion:Deranged lipid profile was found to be associated with the increased cIMT and with occurrence of ischemic stroke. Hence, estimation of cIMT and blood lipid component can help in early manifestation of risk of stroke.