CORRELATION OF CORD BLOOD MALONDIALDEHYDE WITH BIRTH WEIGHT AND PLACENTAL WEIGHT IN NEWBORNS

Dr.B.Durga Mahita; Dr.Roshan Maben

Volume : V, Issue : VII, July - 2016

CORRELATION OF CORD BLOOD MALONDIALDEHYDE WITH BIRTH WEIGHT AND PLACENTAL WEIGHT IN NEWBORNS

Dr. B. Durga Mahita, Dr. Roshan Maben

Abstract :

Background: Oxidative stress injury has been linked with some clinical conditions in newborn. Measuring placental and birth weight along with other features may help in predicting likelihood of oxidative stress injury,babies have suffered. Lipid peroxides are unstable indicators of oxidative stress in cells that decompose to form more complex and reactive compounds such as Malondialdehyde(MDA) bi–product of lipid peroxidation. Aim : To measure birth weight and placental weight of new born babies as well as determining cord blood malondialdehyde levels (product of oxidant injury). Methods: Seventy two term newborns were recruited into the study. Their birth weight and placental weight are recorded and serum cord blood was used for the determination of MDA and uric acid. MDA levels were measured using ELISA Kit. Results: There were positive correlations between placental weight and uric acid and between birth weight and uric acid. There were significant negative correlations between placental weight and MDA. Conclusion:The weight of the placenta is negatively correlated with cord blood MDA.