Correlation of coronary angiography findings with Hba1c levels in patients with acute coronary syndrome.

Dr.Keshavkumar Majjari; Dr. Monarch Shah; Dr. Mounika Bolisetty

Volume : V, Issue : XI, November - 2016

Correlation of coronary angiography findings with Hba1c levels in patients with acute coronary syndrome.

Dr. Keshavkumar Majjari, Dr. Monarch Shah, Dr. Mounika Bolisetty

Abstract :

Diabetes mellitus(DM) is one of the commonest disease worldwide ranking next to cardiovascular disorder. It is estimated that around a 100 million population is affected by diabetes worldwide. Diabetes is a disease of complications, both acute and chronic. Cardiac affliction is by far the commonest cause of mortality in patients with diabetes. Coronary artery disease alone accounts for the major chunk of mortality in diabetes. Glycated hemoglobin (HbA1c) is an established marker for evaluating glucose level at an intermediate term, as it reflects the average plasma glucose control over a period of 2–3 months. Several observational studies demonstrated that a higher HbA1c level was associated with increased risks of cardiovascular diseases and deaths. Although coronary artery disease and diabetes mellitus have been recognized as distinct entities for many decades, but their correlation was established only in 1870 after the work of Seegen J, Der. who emphasized higher incidence and mortality of Coronary artery disease among diabetics Although the patient�s history, physical examination and non–invasive techniques like resting ECG, Holter monitoring, stress test, stress echocardiography, stress thallium imaging are valuable in establishing the diagnosis of acute coronary syndrome in diabetes; coronary angiography or arteriography remains the gold–standard technique for diagnosing and evaluating coronary artery disease. Hence, this study was undertaken and an attempt was made to correlate Hba1c levels in patients presenting with acute coronary syndrome with special interest on their angiographic profile