Correlation of Hba1c levels with clinical outcomes in patients with acute coronary syndrome.

Dr.Keshavkumar Majjari; Dr. Monarch Shah; Dr. Mounika Bolisetty

Volume : V, Issue : VI, June - 2016

Correlation of Hba1c levels with clinical outcomes in patients with acute coronary syndrome.

Dr. Keshavkumar Majjari, Dr. Monarch Shah, Dr. Mounika Bolisetty

Abstract :

 Diabetes mellitus is a well–recognized risk factor for cardiovascular disease and diabetic individuals with acute coronary syndrome (ACS) have a two– to fourfold increased risk of adverse cardiovascular events compared to non–diabetic individuals.6 The presence of elevated blood glucose levels, diabetes mellitus, or both contributes to more than 3 million cardiovascular deaths worldwide each year.8 Although admission glucose has good prognostic value on outcome in ACS, it may be affected by meals, the circadian cycle, and also the stress response On the other hand Glycated hemoglobin A1c (HbA1c) is a better marker of sugar control, as it provides a good reflection of plasma glucose concentrations over 8 to 12 weeks with no effect from meals or the circadian cycle. It also unmasks minor glycometabolic disease, such as impaired glucose tolerance, impaired fasting glucose or metabolic syndrome.16 The primary objective of this study is – To Study the relationship between HbA1c levels and the short–term outcome in patients with Acute Coronary Syndrome (both diabetic and non–diabetic patients).