CORRELATION OF SERUM ALBUMIN, A; G RATIO AND THYRIOD FUNCTION TESTS IN NORMAL PREGNANT WOMEN AND PREECLAMPTIC WOMEN.

DR SUMAIRA CHOWDHARY; DR MASARAT NAZEER; PROF. ANJALI NADIR BHAT

Volume : VII, Issue : VIII, August - 2018

CORRELATION OF SERUM ALBUMIN, A; G RATIO AND THYRIOD FUNCTION TESTS IN NORMAL PREGNANT WOMEN AND PREECLAMPTIC WOMEN.

Dr Sumaira Chowdhary, Dr Masarat Nazeer, Prof. Anjali Nadir Bhat

Abstract :

Aim: The study was done to find out correlation between serum albumin, A;G ratio and thyroid function tests in normal pregnant women and preeclamptic women.

Material and Methods: The present study was done in theDepartment of Physiology, GovernmentMedical College Jammu on 100 pregnant women in second and third trimester of pregnancy. Of the 100 subjects, 50 were preeclamptic women as cases i.e. diseased group (Group I) and 50 normal pregnant women were taken as controls i.e. control group (Group II), w.e.f. November 2014 to October 2015. Total proteins, Serum total Tri–iodothyronine (T3), Tetraiodothyronine (T4), Thyroid Stimulating Hormone (TSH) and serum albumin ,A;G ratio were estimatedin both groups.

Results: Our study shows that Serum TSH is increased significantly while T₃ and T₄ are decreased significantly in preeclampsia as compared to normal pregnancy. Serum albumin is also decreased in preeclamptic women in comparison to normal pregnant women significantly .Also it is seen that relation of serum globulin in preeclamptic and normal pregnant women is not significant (p>0.05). However, total protein and A;G(albumin;globulin) ratio is decreased significantly in preeclamptic women in comparison to normal pregnant women.Hence the correlation of serum albumin with T₃ is significant and direct while with TSH it is significant but inverse.