Correlative Study between Histological Grade and Lymph nodal Metastases in HNSCC

Dr. Ramkishan Gonuguntla; Dr. Arun Kumar Mishra; Dr. Sanjay M Desai; Dr. Deepak Agrawal; Dr. Himanshu Patidar

Volume : VI, Issue : VII, July - 2017

Correlative Study between Histological Grade and Lymph nodal Metastases in HNSCC

Dr. Ramkishan Gonuguntla, Dr. Arun Kumar Mishra, Dr. Sanjay M Desai, Dr. Deepak Agrawal, Dr. Himanshu Patidar

Abstract :

Background: Head and Neck squamous cell carcinoma (HNSCC) are among the top 3 cancers in India and accounts for 30 % of the country�s cancer burden. In this study, we will focus on the lymph nodal metastasis from Head and Neck cancers regarding facts, such as incidence; stage, histopathology and grade of primary tumor. Study design: All patients of head and cancer who were operated in a period of four years in the department of surgical oncology, Sri Aurobindo Medical College & Hospital, Madhya Pradesh, were included in the study. Data is gathered from in patient files, operative records and Histopathology records. Results: Buccal mucosa is the most common site of cancer (42.6%). Incidence is common in male population and male to female ratio is 2.5:1.Most patients presented in middle age and stage IV is the most common presentation. 86.4% of tumors are low grade. High grade tumors presented with advanced stage and more number of metastatic lymph nodes. Conclusion: Location of primary tumor pattern of invasion, histologic grade, disease stage, will influence the lymph node metastasis, and prognosis in HNSCC. Assessments of mentioned parameters are beneficial in selecting patients who need more aggressive treatment modalities.