Volume : III, Issue : VII, July - 2014

Cranberry : a Boon to Periodontium

Dr. Babita Pawar, Dr. P. P. Marawar, Dr. Richa Patel, Dr. Tushar Bhople

Abstract :

Over the past decade, cranberries and their molecular components have received increasing attention from researchers in human health. A non-dialysable cranberry fraction enriched in high molecular weight polyphenols has very promising properties with respect to cariogenic and periodontopathogenic bacteria, as well as to the host inflammatory response and enzymes that degrade the extracellular matrix. Cranberry components are potential anti-caries agents since they inhibit acid production, attachment, and biofilm formation by Streptococcus mutans. Glucan-binding proteins, extracellular enzymes, carbohydrate production, and bacterial hydrophobicity, are affected by cranberry components. Cranberry polyphenols may reduce the inflammatory response, as well as the production and activity of proteolytic enzymes contributing to the destruction of the extracellular matrix in periodontal disease. The polyphenols of cranberries also interfere with various activities of Porphyromonas gingivalis, the main etiologic agent in chronic periodontitis. The unique combination of phytochemicals found in cranberry fruit may produce synergistic health benefits. Possible chemopreventive mechanisms of action by cranberry phytochemicals include induction of apoptosis in tumor cells, reduced ornithine decarboxylase activity, decreased expression of matrix metalloproteinases. This article summarizes the scientific evidence supporting the potential of cranberry polyphenols to prevent and/or treat diseases of oral diseases.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.Babita Pawar, Dr. P. P. Marawar, Dr.Richa Patel, Dr.Tushar Bhople Cranberry : a Boon to Periodontium International Journal of Scientific Research, Vol : 3, Issue : 7 July 2014

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