CURCUMIN ORABASE IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS: A NOVEL APPROACH.

Rama Raju Devaraju; Harisha Aitha; Srikanth Goud Gotoor; Anantha Venkata Srikar Muppirala; Tejaswi katne

Volume : VI, Issue : VI, June - 2017

CURCUMIN ORABASE IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS: A NOVEL APPROACH.

Rama Raju Devaraju, Harisha Aitha, Srikanth Goud Gotoor, Anantha Venkata Srikar Muppirala, Tejaswi Katne

Abstract :

Aims and Objectives: The aim of this study was to evaluate the efficacy of 4% curcumin orabase, in oral submucous fiosis (OSMF). Materials and Methods: 30 subjects diagnosed with OSMF were included for the study. The patients were administered 4% curcumin orabase (Patent no. 845/CHE/2014) topically three times a day; efficacy of the therapy was evaluated considering the mouth opening and burning sensation of the subjects as parameters. The evaluation was done on a timely basis for a period of three months, and the data was then evaluated. Results: The improvement in mouth opening and the decrease in burning sensation were statistically significant (p<0.0001). Conclusion: 4% Curcumin orabase can also be considered as a best alternative treatment in OSMF, however, further research is intended on a larger sample size with longer followup.