Dermatological manifestations in HIV patients and its correlation with CD4 count: A prospective study

Dr. Praveen Thakurai; Dr. Anvesh Singh Parmar

Volume : VII, Issue : V, May - 2018

Dermatological manifestations in HIV patients and its correlation with CD4 count: A prospective study

Dr. Praveen Thakurai, Dr. Anvesh Singh Parmar

Abstract :

Background: More than 90% of human immunodeficiency virus (HIV+) infected patients develop skin lesions at some time throughout the course of the disease. Several skin diseases have proved to be sensitive and useful indicators of progression of HIV+ infection

Aims and Objectives: To study dermatological manifestations in HIV infected patients and to see the correlation with CD4 count.

Materials and Methods: One hundred and fifteen HIV patients were studied at ART Center Medicine Department, GR Medical College, Gwaliorbetween Aug. 2014 to Nov. 2015. Detailed history regarding the epidemiological aspects of the disease (HIV infection) and the dermatological symptoms was taken and thorough physical examination of the patient was performed with emphasis on cutaneous manifestations.

Results: Male preponderance was observed (68.69%). Most of the patients were manual laborers (48.69%), belonged to urban population (74.78%), from lower income group (59.13%), were (88.69%) were married and had (38.26%) primary education.Most of the patients(50.43%) had CD4 count between 200–350. Among viral infection herpes zoster, molluscumcontagiosum, herpes genitalis and herpes labialis had CD4 count of 271, 291, 263 and 178 respectively. Among fungal infection candidiasis, andtineacorporis/crurishad CD4 count of 325 and 256 respectively. Pyogenic bacterial infections had CD4 count of 363 whereas patients with scabieshad CD4 count between 200–380.

Conclusion:Skin problems were common among HIV positive patients. Patients with advanced stages of skin disorders had relatively lower CD4 counts. Therefore, examination of skin disorders, as early diagnosis and management of dermatologic problems will improve the quality of life in HIV positive patients.