Volume : IV, Issue : X, October - 2015

Dexmedetomidine: A simple, easy, and economical adjuvant for general anesthesia

Dr. Anita B. Patel, Dr. Lisa Abraham

Abstract :

CLINICAL REASECH ARTICAL Dexmedetomidine (Dex), a specific ∝2–adrenergic agonist, has sedative,analgesic and anxiolytic, properties This study examined the effect of dexmedetomidine on sedation, hemodynamic values, anesthetic consumption, and recovery from anesthesia. Forty–two female patients undergoing gynaecologic surgery were randomly assigned to receive IV Dex(1µg/kg: Dex group) or saline (control group) over 10min before anestbetic induction. After tracbeal intubation, anestbesia was maintained with sevoflurane, o2 (50%) N2o(50%). Mean arterial pressure(MAP) and heart rate(HR) after intubation were increased in Control group, but did not change in the Dex group. The HR of the Dex group was lower compared to that of the Control group during maintenance; no difference in MAP between the groups. End–tidal concentration and total cumulative consumption of sevoflurane were lower in the Dex group than in the control group. Recovery profiles, postoperative nausea, voming, and visual analogue pain score were not significantly different between the groups. In conclusion, single infusion of Dex(1 µg/kg) is a simple, easy and economical adjuvant for general anesthesia. Dex maintains stable hemodynamics and decreases anestbetic consumption without changing recovery profiles.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR. ANITA B.PATEL, DR. Lisa Abraham Dexmedetomidine: A simple, easy, and economical adjuvant for general anesthesia International Journal of Scientific Research, Vol : 4, Issue : 10 October 2015

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