DIAGNOSTIC ACCURACY OF XPERT–MTB/RIF ASSAY IN GENITOURINARY TUBERCULOSIS

Suryakant Choubey; Revanasiddappa A Kanagali; A Nagaraj Rao; Goutam Pipara

Volume : VII, Issue : I, January - 2018

DIAGNOSTIC ACCURACY OF XPERT–MTB/RIF ASSAY IN GENITOURINARY TUBERCULOSIS

Suryakant Choubey, Revanasiddappa A Kanagali, A Nagaraj Rao, Goutam Pipara

Abstract :

Genitourinary tuberculosis is still a major health problem in many developing countries including India and the diagnosis requires the availability of diagnostic tools that allow the rapid detection of M. Tuberculosis.

Objective: To determine the sensitivity and specificity of Xpert MTB/RIF Assay in the diagnosis of genitourinary tuberculosis.

Methods: A prospective study wherein the urine samples of patients with suspected GUTB, were subjected to XpertMTB/RIF assay and AFB culture. The XpertMTB/RIF assay was compared with AFB urine culture which is considered gold standard and sensitivity and specificity was calculated.

Results: The results of XpertMTB/RIF assay for 231 samples were compared with those of cultures. The sensitivity of the XpertMTB/RIF assay was 83.3% and the speciﬁcity was 100%.

Conclusion: The GeneXpert assay is a useful rapid diagnostic test for both pulmonary and EPTB including GUTB.