Diagnostic Evaluation of Gene Xpert Mycobacterium tuberculosis Assay for the Detection of Rifampicin Resistant Mycobacterium tuberculosis among Pulmonary Patients of South Zone of Odisha

Satyaram satapathy; Debashish Samal; Pratikshya Das

Volume : V, Issue : XI, November - 2016

Diagnostic Evaluation of Gene Xpert Mycobacterium tuberculosis Assay for the Detection of Rifampicin Resistant Mycobacterium tuberculosis among Pulmonary Patients of South Zone of Odisha

Satyaram Satapathy, Debashish Samal, Pratikshya Das

Abstract :

Tuberculosis remains a major global health problem. It ranks as the second leading cause of death from an infectious disease worldwide. Our aim was to evaluate the performance of GeneXpert system for the detection of Mycobacterium tuberculosis with its Rifampicin resistance within shortest possible time. Our assay can simultaneously confirm the presence of M. Tuberculosis and detect the mutations associated with resistance to anti–TB drugs, there by diagnosing M/XDR–TB with good sensitivity and specificity.