Diagnostic utility of computed tomography guided fine needle aspiration cytology in lung lesions.

Dr. Neepamanjari Barman; Prof. (Dr.) Ranu Sarkar; Dr Swapanendu Misra; Dr Moumita Paul; Dr Moumita Maiti

Volume : VIII, Issue : XI, November - 2019

Diagnostic utility of computed tomography guided fine needle aspiration cytology in lung lesions.

Dr. Neepamanjari Barman, Prof. Dr. Ranu Sarkar, Dr Swapanendu Misra, Dr Moumita Paul, Dr Moumita Maiti

Abstract :

Introduction: Lung is a common site for many infectious, benign and malignant lesions and they can be accurately diagnosed using CT guided FNAC.It is not only complement the tissue biopsies in the diagnosis of lung lesion, but also comparable. Moreover, it is safer, economical and provides quick results and patient can get relived from apprehension in a case of non malignant lesion. Aims & Objectives: 1. To study the spectrum of cytomorphology of the lung lesions 2. Toevaluate the effectiveness of CT‑guided FNAC in the diagnosis of lung lesions. Material and methods: A cross–sectional and observational study was carried out over a period of one year in the Department of Pathology, NRS Medical College, and Kolkata. It involved 97 patients who had undergone CT guided FNAC for lung lesions and the cytology smears were stained with MGG stain and Pap stain. The cytological diagnosis was compared with subsequent histopathology report of 78 cases .Results were analyzed using standard statistical formula. Results: Among the study population , 74.2% were males. 46.4% were in the age group of 61–70 years . Cough was the most common presenting symptom ( 36.08%); Mass lesion (55%) was the most common radiological findings . Among72 malignant lesions, adenocarcinoma was the most common malignancy(43.29 %), In 78 cases histological reports were compared with cytology which had 97.50% sensitivity,98.75% specificity, 98.73% positive predictive value , 97.53% negative predictive value and 98.12% accuracy for CT guided FNAC as a diagnostic procedure and Fleiss Kappa coefficient is 0.48. between cytology and histology. Conclusion: CT guided FNAC is a safe, effective , relatively simple procedure with a good sensitivity, specificity, high accuracy rate and moderately fair agreement with biopsy in diagnosing pulmonary lesions .