Diagnostic Utility of Typhoid Elisa Test In Comparison to Other Conventional Methods for Diagnosis of Typhoid Fever

Dr. Neha Makwana; Dr. Pratik R. Shah; Dr. Madhulika Mistry; Dr. Yogesh Goswami

Volume : III, Issue : VII, July - 2014

Diagnostic Utility of Typhoid Elisa Test In Comparison to Other Conventional Methods for Diagnosis of Typhoid Fever

Dr. Neha Makwana, Dr. Pratik R. Shah, Dr. Madhulika Mistry, Dr. Yogesh Goswami

Abstract :

Typhoid fever is endemic in many parts of the world and continues to be one of the leading causes of morbidity and mortality in our country. We have studied typhoid IgM ELISA test, a rapid serological test for diagnosis of typhoid fever and its usefulness for an early diagnosis, its sensitivity and specificity as compared to widal test. Out of 100 samples 22 (22%) cases were positive by blood culture, 30 (30%) were positive with Widal test and 36 (36%) were positive with typhoid ELISA test. The sensitivity, specificity, positive and negative predictive value of Widal test was 63.6%, 79.4%, 46.6% and 88.5% respectively. The sensitivity, specificity, positive and negative predictive value of typhoid IgM ELISA test was 95.4%, 80.7%, 58.3% and 98.4% respectively proving the superiority of typhoid IgM ELISA test.