Differential diagnoses of sarcoidosis and primary Sjogren syndrome: A case report

Jijin Mekkadath Jayakrishnan; Hombarvali Puttabuddi Jaishankar; Shashidara Raju; Libina Isahak; Ramachandran Anjana

Volume : VI, Issue : IX, September - 2017

Differential diagnoses of sarcoidosis and primary Sjogren syndrome: A case report

Jijin Mekkadath Jayakrishnan, Hombarvali Puttabuddi Jaishankar, Shashidara Raju, Libina Isahak, Ramachandran Anjana

Abstract :

Due to unavailability of diagnostic facilities and resemblance with other diseases such as tuberculosis, Sjogren syndrome, and xerostomia, sarcoidosis is underreported in developing countries, including India. We have reported a 47–year–old woman who presented with dryness of the mouth for past 5 months suggestive of Sjogren syndrome. However, biochemical analysis revealed high level (233 U/L) of angiotensin–converting enzyme, which confirmed the diagnosis of sarcoidosis. The diagnosis was further supported by the presence of noncaseating granuloma and lymphocytic infiltrate on salivary gland biopsy. Also, X–ray and computed tomography of the chest revealed bilateral submandibular lymphadenopathy, which is suggestive of sarcoidosis. Currently the patient is under medication and prognosis is good.