Volume : III, Issue : X, October - 2014

DPPH Free Radical Scavenging Activity of Different Extract of Eclipta alba.

Bindia Sahu

Abstract :

Plant & plant products are being used as a source of medicine since a long period in our country. Natural products are organic compound that are synthesized by the plants as secondary metabolites to protect them from insect, pest, or other environmental conditions.The medicinal value of plants was to see chemical substances that produce a definite psychological action on the human body. The most important of these bioactive compounds of plants are alkaloids, flavonoids, tennis, and phenolic compounds. Flavonoids have been reported as an antioxidant. Majority of the disease are mainly linked to the oxidative stress due to free radicals. Free radicals are fundamental to any biochemical process and represent an essential part of aerobic life &metabolism the most common reactive oxygen species (ROS) include (O2–) anion, hydrogen peroxide (H2O2), (ROO–) radicals & reactive (OH–) radicals. The nitrogen derived free radicals are, nitric oxide (NO) & (ONOO–) anion. ROS have been implicated in over a 100 of disease which range from arthritis & connective tissue disorder to carcinogenesis, ageing physical energy infection & acquired immune deficiency syndrome. Antioxidants play a very important role in the therapy of these diseases. The DPPH method applies to the overall antioxidant capacity of the sample. DPPH is relatively stable free radical and the method determines the ability of acetone extract of plant to reduce the DPPH radical to the corresponding hydrazine by reacting with the hydrogen donors in the antioxidant principles. . Ethanolic extracts of E. alba exhibited better antioxidant potential in comparision to ascorbic acid as evidenced by lower IC50values respectively in DPPH assay.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Bindia Sahu DPPH Free Radical Scavenging Activity of Different Extract of Eclipta alba. International Journal of Scientific Research, Vol : 3, Issue : 10 October 2014

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