Volume : VI, Issue : II, February - 2017

DYNAMIC SUSCEPTIBILITY CONTRAST ENHANCED MRI PERFUSION IMAGING IN EVALUATION OF POST CHEMO – RADIOTHERAPY TREATED GLIOMAS FOR RECURRENCE COMPARISON WITH RESPONSE ASSESSMENT CRITERIA

Dr Gurdarshdeep Singh Madan, Col Giriraj Singh, Brig S Bhatnagar, Dr Bk Chakrabarty

Abstract :

 Aim: To compare Dynamic Susceptibility Contrast Enhanced (DSC) Magnetic Resonance Perfusion Imaging with clinicoradiological response criteria in post chemoradiotherapy treated gliomas.

Materials and Methods: Forty patients of histologically proven gliomas were chosen post chemoradiotherapy and were evaluated MRI perfusion The findings were correlated with clinico radiological response criteria.

ResultsThere was statistical good correlation with all the response criteria in complete response and partial response subset (p value <0.001). However, DSC MRI showed good correlation with RANO Criteria (Pearson Correlation = .642 and 2 tailed significance p value = 0.002). The correlation with other response criteria were not statistically significant.

Conclusion:  RANO Criteria is the presently accepted clinico–radiological criteria which has superseded other response criteria and DSC MRI perfusion imaging shows statistically good correlation among all the subset of responses.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Gurdarshdeep Singh Madan, Col Giriraj Singh, Brig S Bhatnagar, Dr BK Chakrabarty, DYNAMIC SUSCEPTIBILITY CONTRAST ENHANCED MRI PERFUSION IMAGING IN EVALUATION OF POST CHEMO – RADIOTHERAPY TREATED GLIOMAS FOR RECURRENCE COMPARISON WITH RESPONSE ASSESSMENT CRITERIA, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-2 | FEBRUARY-2017

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