Volume : VIII, Issue : VII, July - 2019

Effect of addition of clonidine to intrathecal bupivacaine in spinal anaesthesia for orthopaedic surgeries

Dr. Hansraj Charan, Dr. B. P. Tripathi, Dr. Chiranji Lal Khedia

Abstract :

Introduction–: Spinal anaesthesia is one of the most common approaches for most of lower limb surgeries. Clonidine has been recently introduced in India in the parenteral form (Cloneon, Neon laboratories). Hence there is a need to study its effects when used along with hyperbaric Bupivacaine, through intrathecal route. Therefore, this study was designed to study the effect of clonidine at different doses as an adjuvant to hyperbaric Bupivacaine, given intrathecally in orthopaedic surgeries. Aims and objectives–: To evaluate the efficacy of intrathecal Clonidine in low doses (25 µg and 50 µg) as adjuvants to 0.5% hyperbaric Bupivacaine 12.5 mg for spinal anaesthesia in orthopaedic surgeries. Methodology–: Ninety patients planed to undergo orthopaedic surgeries were subjected to this study. They were randomly divided into three groups of thirty each. Group A: Bupivacaine heavy (0.5%) 2.5 ml + No Clonidine, Group B: Bupivacaine heavy (0.5%) 2.5 ml + 25µg Clonidine, Group C: Bupivacaine heavy (.5%) 2.5ml + 50µg Clonidine Results and conclusion–: Intrathecal administration of preservative free clonidine 25 mcg and 50 mcg along with 0.5% Bupivacaine significantly prolongs the duration of sensory and motor blockade. Significant prolongation of post–operative analgesia occurs with 50 mcg clonidine. Patients with 50 mcg clonidine remains calm, comfortable, minimally sedated throughout procedure with easily arousable with minimum hemodynamic instability like hypotension and adycardia which can be easily managed.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

EFFECT OF ADDITION OF CLONIDINE TO INTRATHECAL BUPIVACAINE IN SPINAL ANAESTHESIA FOR ORTHOPAEDIC SURGERIES, Dr. Hansraj Charan, Dr. B. P. Tripathi, Dr. Chiranji Lal Khedia INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-7 | July-2019

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