Volume : VII, Issue : X, October - 2018

EFFECT OF AGE ON LIPID PROFILE IN CHRONIC KIDNEY DISEASE

Manpreet Saini, Gurpreet Kaur, Nita Garg

Abstract :

Aim:The aim of this study was to establish a correlation & find effect of Age on Serum T.Cholestrol, HDL,LDL, TG, T.Cholestrol/HDL ratio & LDL/HDL ratio of Chronic kidney disease patients. Study Design:A hospital based Non–Experimental Observational Cross–sectional & Correlation Study was conducted on patients of both sex attending the Out Patient Department & In Patient Department of Nephrology & Medicine of SMI Hospital, P.Nagar Dehradun for a period of 4 months from January 2014 to April 2014. Study comprises 54 Chronic kidney disease patients which were divided into five age groups i–e Age group– 15–29yrs, Age group– 30–44yrs, Age group–45–59yrs, Age group– 60–74yrs, Age group– ≥75yrs. Inclusion criteria was patients with evidence ofChronic kidney disease selected randomly of both sex & age above 15 years. Exclusion criteria was age <15 years & those not willing to participate. Methdology:Consecutive sampling technique &Bio–physiological method of collection of Data was used .5ml blood was collected in sterile tubes from the fasting (8–12hrs) test group & was analyzed for Serum T.Cholestrol, HDL,LDL, TG, T.Cholestrol/HDL ratio & LDL/HDL ratio by enzymatic method using VITROS ECIQ,an auto analyser at SMI Hospital,P.Nagar, Dehradun.Correlation coefficient i–e r–value & p–value was analysed using Microsoft office Excel 2007.Positive r– value represented positive correlation between that age group & that parameter & vice versa. P<0.05 was considered significant & P<0.01was considered highly significant Results:Age group 15–29yrswas found to have negative Correlation coefficient with S. HDL,VLDL,TG, T.chol/HDL, LDL/HDL& positive Correlation coefficient with T.Chol, LDL values of Chronic kidney disease patients. Relationship of HDL,VLDL,TG,T.Chol/HDL was found to be Non significant (P>0.05)& S. T.Chol, LDL, LDL/HDL was found to have significant (P<0.05) relationship with this Age group. Age group 30–44yrs was found to have negative Correlation coefficient with S. HDL,T.Chol,VLDL,TG, & positive Correlation coefficient with T.chol/HDL, LDL/HDL, LDL values of Chronic kidney disease patients. Relationship of HDL,VLDL was found to be Non significant (P>0.05) & S. T.Chol, TG was found to have significant (P<0.05) relationship, LDL,T.Chol/HDL,LDL/HDL ratio was found to have Highly significant (P<0.01) relationship with this age group. Age group 45–59yrswas found to have negative Correlation coefficient with S.T.Chol,LDL,T.Chol/HDL,LDL/HDL, & positive Correlation coefficient with HDL,TG, VLDL values of Chronic kidney disease patients. Relationship of S. T. Chol, LDL,VLDL,TG,T.ChoL/HDL,LDL/HDL was found to be Non significant (P>0.05) & HDL  was found to have Highly significant (P<0.01) relationship with this age group. Age group 60–74yrs was found to have negative Correlation coefficient with HDL, & positive Correlation coefficient with S.T.Chol, LDL,VLDL, TG, T.Chol/HDL,LDL/HDL ratio values of Chronic kidney disease patients. Relationship of S. T.Chol,LDL,VLDL,T.ChoL/HDL,LDL/HDL was found to be Non significant (P>0.05) & HDL,TG  was found to have Highly significant (P<0.01) relationship with this age group. Age group ≥75yrs was found to have negative Correlation coefficient with S.T.Chol, LDL,TG, T.Chol/HDL,LDL/HDL ratio & positive Correlation coefficient with HDL,VLDLvalues of Chronic kidney disease patients. Relationship of LDL,VLDL,T.ChoL/HDL,LDL/HDL was found to be Non significant (P>0.05) &S. T.Chol HDL,TG  was found to have Highly significant (P<0.01) relationship with this age group.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Manpreet Saini, Gurpreet Kaur, Nita Garg, EFFECT OF AGE ON LIPID PROFILE IN CHRONIC KIDNEY DISEASE, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-10 | October-2018

Number of Downloads : 100

References :