Volume : VIII, Issue : VI, June - 2019

Effect of Brahmi Ghrita on neuro–inflammation in MCI due to Alzheimer‘s Disease

Richa Tripathi, J. S. Tripathi

Abstract :

The transitional stage between the cognitive changes of normal ageing and dementia is known as “Mild cognitive impairment” (MCI). MCI due to Alzheimer’s disease is also an intermediated stage in the process of Alzheimer’s disease. Although vigorous research is going all over the world, the exact diagnosis as well as the most hopeful therapy i.e. disease alteration therapy is being compromised because of lack of biomarkers and other pathologic events. Significant evidence suggests that inflammation has a contributory role in Alzheimer’s Disease pathogenesis1,2 and understanding and control of interactions between the immune system and nervous system might be key to prevention or delay of disease 3,4. In Alzheimer’s Disease, neuro–inflammation plays almost equal role to the pathogenesis as senile plaques and neuro fiillary tangles (NFTs). TNF–α5, is one of the main inflammatory cytokines and Interleukin 10 (IL–10) is an anti–inflammatory cytokine involved in initiating and propagating an inflammatory response. This study shows the positive response of a Brahmi Ghrita (polyherbal Ayurvedic formulation) on these inflammatory markers.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

EFFECT OF BRAHMI GHRITA ON NEURO-INFLAMMATION IN MCI DUE TO ALZHEIMER'S DISEASE, Richa Tripathi, J. S. Tripathi INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-6 | June-2019

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