Effect of Glycemic control on Brain Stem Auditory Evoked Potential (BAEP) based on HbA1c in TYPE II Diabetes Mellitus.

Dr. Taruna; Dr. Mohammad Zakiuddin

Volume : VIII, Issue : VIII, August - 2019

Effect of Glycemic control on Brain Stem Auditory Evoked Potential (BAEP) based on HbA1c in TYPE II Diabetes Mellitus.

Dr. Taruna, Dr. Mohammad Zakiuddin

Abstract :

BACKGROUND: Diabetes mellitus is a complex metabolic disorder whose detrimental effects on various organ systems, including the nervous system are well known. Diabetes mellitus is becoming one of the most important health problems not only in developed countries but also in developing countries. Neuropathy is a common and frustrating long–term complication of diabetes. Diabetes may alter both the peripheral and central nerve functions but the peripheral manifestations of diabetic neuropathy are more frequently discussed in the literature than the impairment of cranial nerves. MATERIAL AND METHODS: In the present study 90 subjects were enrolled considering the inclusion and exclusion criteria. They were divided into 3 groups Diabetics, Prediabetics, and Controls Evoked potentials offer the possibility to perform a functional evaluation of neural pathways in the central nervous system neurons. One of these methods is Brainstem Auditory Evoked Potentials (BAEPs). By this method, functional pathologies from the acoustic nerve to the upper part of ain stem and auditory cortex can be demonstrated at early stage. These are objective and non–invasive methods of investigation. RESULT: Their HbA1c & BAEP was assessed. On comp� Glycemic levels based on HbA1c with BAEP of left ear we found a statistically increase in BAEP latency of wave III in uncontrolled diabetics as compared to controls, Prediabetics and controlled diabetics. (3.89�.06 ms vs. 3.63�.20 ms, 3.63�.28 ms and 3.69�.22 ms p < .01).But we found no statistically significant difference in comp� HbA1c with BAEP of right ear. Conclusion: Our study showed that in diabetes patients of less than 5 yrs, with poor Glycemic control there was a unilateral abnormality of superior olivary nucleus in pons in auditory pathway, which may be interpret as beginning of central neuropathy in these diabetic patients. So this reveals that central neuropathy in auditory pathway begins earlier with poor Glycemic control. Maintaining good Glycemic control is very important in diabetes, as poor Glycemic control, even in short duration of diabetes, can lead to he� loss.