Volume : VIII, Issue : VI, June - 2019
Effect Of Neuronal Nicotinic Acetylcholine Receptor Gene Polymorphism In Development Of Febrile Seizure
Sayani Banerjee, Satwika Sinha
Abstract :
Background : Among all childhood seizure patients feile seizure accounts for more than 30% of the total. A lot of confounding factors are there in the causation of feile seizure. We designed this study to investigate the mutation in receptor neuronal nicotinic acetylcholine gene to determine whether this polymorphism could be a marker of susceptibility to feile seizure in children. Materials and methods: 100 case and 100 age and sex matched healthy controls were selected. Fasting blood samples were collected. Data was analyzed statistically. Results: Genetic variations in nicotinic acetylcholine gene was found among the feile seizure patients. Discussion: Any mutation in the coding region of the receptor protein might effect their production and resulted in feile seizure. Conclussion: Treating the patient a gene analysis may give prior information and can decrease the morbidity and future complications to the patient and the related family members.
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DOI : 10.36106/ijsr
Cite This Article:
EFFECT OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR GENE POLYMORPHISM IN DEVELOPMENT OF FEBRILE SEIZURE, Sayani Banerjee, Satwika Sinha INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-6 | June-2019
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References :
EFFECT OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR GENE POLYMORPHISM IN DEVELOPMENT OF FEBRILE SEIZURE, Sayani Banerjee, Satwika Sinha INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-6 | June-2019
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