Effect of Syzygium cumini (jamun) seed powder on blood pressure in patients with type 2 diabetes mellitus – a double blind randomized control trial

Shivani Sidana; Veer Bahadur Singh

Volume : V, Issue : III, March - 2016

Effect of Syzygium cumini (jamun) seed powder on blood pressure in patients with type 2 diabetes mellitus – a double blind randomized control trial

Shivani Sidana, Veer Bahadur Singh

Abstract :

BACKGROUND: Hypertension is a common comorbidity in patients with type 2 DM, contributing to morbidity and mortality associated with disease, demanding control of both hyperglycemia and hypertension. Antihyperglycemic effect of Syzygium cumini seed powder is proved by many studies, but not sufficient data till date available for its antihypertensive effect, which should also be ought into light. AIMS AND OBJECTIVES: To study effect of jamun seed powder on blood pressure in type 2 diabetes mellitus. MATERIAL AND METHODS: Patients with type 2 DM (n=99) were randomly divided in two groups– group A (n=50) was supplemented with 10 gms/day jamun seed powder and group B (n=49) was given placebo powder. Patients and investigators were blinded about treatment allocated. S.B.P. and D.B.P. were noted at baseline and 30th, 60th and 90th day. All the data was collected and analyzed at the end of study. STATATISTICAL ANALYSIS: critical difference was calculated using one way ANOVA through INDOSTAT software and two groups were compared using t–test through MSTAT software. OBSERVATIONS AND RESULTS: It was observed that mean S.B.P. of group A reduced significantly from 152�17.14mmHg to 145�15.47mmHg, 143�14.41mmHg and 140�13.23mmHg after supplementation with jamun seed powder for 30, 60 and 90 days respectively. Mean D.B.P. of group A reduced significantly from 91�13.57mmHg to 86�11.60mmHg and 85�3.91mmHg after 60 and 90 days respectively. No significant change was observed in S.B.P. and D.B.P. of group B. CONCLUSION: Supplementation with jamun seed powder significantly lowers the blood pressure of patients with type 2 diabetes mellitus besides its known antihyperglycemic effects. Thus it help in improving overall health of diabetic patients. However, before recommendation multicentric trial with larger sample size, dose and duration should be planned.