Effect of Tobacco Leaf Paste on The Histoarchitecture of The Reproductive System of The Male Albino Mice

PawlinVasanthi Joseph

Volume : III, Issue : XII, December - 2014

Effect of Tobacco Leaf Paste on The Histoarchitecture of The Reproductive System of The Male Albino Mice

Pawlinvasanthi Joseph

Abstract :

Oral cancer is a problem of paramount importance due to its high incidence in India and its statistically significant relationship with chewing tobacco. The testis controls a myriad of functions in the male.Spermatogenesis is affected in a variety of ways when the testis is subjected to different physiological treatments.The present work aims to study the effect of tobacco paste painting on the spermatogenic activity of the testis, since a part of the painted tobacco paste gets ingested by the animal into the gut. Experiments were designed to include a group which received vitamins in addition to the normal diet, in order to find out whether the addition of vitamins has any reducing effect on the toxic effect of painting tobacco paste.A significant decrease in the spermatogenic stages of the testis was observed in both the experimental groups. The findings suggest that oral tobacco paste painting on mice significantly alters the histology of the testes and epididymis