EFFECTS OF INFUSION OF MAGNESIUM SULPHATE ON HEMODYNAMIC PARAMETERS, OCCURRENCE OF ARRHYTHMIAS, ANAESTHETIC REQUIREMENT, POST OPERATIVE OUTCOME IN CORONARY ARTERY BYPASS GRAFTING

DR.REEMA MEENA; DR.VASUNDHARA; DR.CHETAN GOYAL

Volume : VI, Issue : VI, June - 2017

EFFECTS OF INFUSION OF MAGNESIUM SULPHATE ON HEMODYNAMIC PARAMETERS, OCCURRENCE OF ARRHYTHMIAS, ANAESTHETIC REQUIREMENT, POST OPERATIVE OUTCOME IN CORONARY ARTERY BYPASS GRAFTING

Dr. Reema Meena, Dr. Vasundhara, Dr. Chetan Goyal

Abstract :

Patients undergoing off pump Coronary bypass surgery are prone to have hemodynamic instability,intraoperative and postoperative arrythmias and myocardial infarction. So, many agents are used to overcome this response. Magnesium is one of them,it is an important determinant of resting memane potential of cardiac cell memane. Objective:–This study was aimed to determine the efficacy of magnesium sulphate on hemodynamic parameters, occurrence of arrythmias, anaesthetic requirement and postoperative outcome in OPCABG. Methodology:–80 patients of either sex(25–60 yr of age)undergoing elective off pump coronary artery bypass grafting were randomly allocated to 2 groups(40 in each group).Patients of group A received infusion of magnesium sulphate 50mg/kg in 100ml saline over 15 min before induction and then 15mg/kg/hr till end of surgery while group C patients received infusion of normal saline of same calculated volume as of drug infusion. Results:–Pulse rate and blood pressure in patients of group A were significantly low from baseline compared to group C at all study point. Similar BIS value were achieved at lower fentanyl dose, both during induction and intraoperatively in patients of group A compared to group C and analgesic dose requirement was also low in group A. Conclusion:–Magnesium sulphate is effective in stabilizing the hemodynamics of patients during surgery,less incidences of ST segment elevation and ventricular arrythmias, reduced anaesthetic drug consumption and improved postoperative recovery.