Volume : III, Issue : V, May - 2014

Efficacy of Fixed dose combination of Formoterol and Fluticasone propionate dry powder inhaler (DPI), in management of Partly controlled & Uncontrolled asthma in 5–17 yr group

Mohammad Shameem Md, Jamal Akhtar, Asrar Ahmad, Jameel Ahmad

Abstract :

It has been found that compositions containing formoterol and fluticasone propionate induce an anti–inflammatory activity which is significantly greater than that induced by formoterol or fluticasone propionate aloneThis was an open label, prospective, non–comparative, multicenter study of  patients 149, 5–17years old, diagnosed with �Partly controlled & uncontrolled� asthma, treated for 8 weeks with twice daily fixed dose combination of fluticasone and Formoterol DPI capsules (rheocaps), inhaled using DPI device (rheohaler). Asthma  control was assessed by changes in FEV1, FVC, PEFR, validated 5–item Asthma Control test (ACT) & patient/physician global assessments. Spirometry was performed by Easy–on PC Spirometer (made Switzerland) Partly controlled Asthma was defined as daytime symptoms are occurring more than twice a week, sometimes at night and occasionally they limit activity. Quick–relief medicine is needed more than twice a week. Peak flow rate is less than 80 percent of your personal best, and asthma attacks occur at least once a year(GINA Guidelines 2012). Uncontrolled Asthma was defined as uncontrolled if patients have 3 or more of the features of partially controlled asthma at least 3 times a week, and asthma attacks are occurring weekly(GINA Guidelines 2012). 

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Mohammad Shameem MD, Jamal Akhtar, Asrar Ahmad, Jameel Ahmad /Efficacy of Fixed dose combination of Formoterol and Fluticasone propionate dry powder inhaler (DPI), in management of “Partly controlled & Uncontrolled” asthma in 5-17 yr group /International Journal of Scientific Research, Vol.3, Issue. 5, May 2014

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