Efficacy of topical Tranexamic acid on blood loss during open Myomectomy a randomized controlled trial

Dr. S. Karpagam; Dr. P Bakiavathy

Volume : IX, Issue : VI, June - 2020

Efficacy of topical Tranexamic acid on blood loss during open Myomectomy a randomized controlled trial

Dr. S. Karpagam, Dr. P Bakiavathy

Abstract :

Objectives: To assess efficacy of topical tranexamic acid in reducing intra–operative blood loss in open myomectomy surgeries. Materials and methods: 100 women who underwent open Myomectomy were randomly divided into two groups. The ﬁrst group received 2 gm topical tranexamic acid applied on myoma bed after myomectomy and the second group received topical placebo. Results: Topical tranexamic acid application significantly reduced intra–operative blood loss compared to placebo (305.24 � 56.21 ml vs 523.57� 62.38 ml) and it was statistically signiﬁcant (P < 0.0001). Conclusion: Topical application of tranexamic acid significantly reduced intra–operative blood loss during open Myomectomy.