Volume : V, Issue : III, March - 2016

EFFICACY OF TRANEXAMIC ACID IN REDUCING PERIOPERATIVE BLOOD LOSS DURING CAESAREAN SECTION: A PLACEBO CONTROLLED DOUBLE BLIND STUDY

Dr. Amrita Gupta, Dr Yogita Dwivedi, Dr. Vivek Shakya, Dr Uma Srivastva, Dr Avanish Saxena, Dr Atiharsh Mohan Agarwal, Dr. Sandeep Mangla

Abstract :

 Introduction: caeserian section is one of the most common surgeries in women of child beå age. With this study we are emphasizing the effect of tranexamic acid in reducing blood loss after caeserian section. Method: a total number of 102 parturients aged 20 –40 years with singleton fetus,38 or more weeks of pregnancy were selected for the study. They were divided into two groups – Group T who received 1 gm tranexamic acid diluted with 20 ml of 5 % dextrose which was given 20 min before skin incision. In Group P ,patient received 20 ml of 5 % dextrose. Hemodyanamic variables , amount of blood loss, apgar score and any adverse effects were noted. Results: in this randomized controlled study , tranexamic acid significantly reduce the blood loss. Patients in Group T had higher mean hematocrit level postoperatively. haemodyamic variables were comparable in both the groups. No significant adverse effects were seen related to tranexamic acid administration.APGAR score was comparable in both the groups. Conclusion: Tranexamic acid significantly reduce bleeding after caeseran section without increase in incidence of thromboembolic events.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Amrita Gupta, Dr Yogita Dwivedi, Dr. Vivek Shakya, Dr Uma Srivastva, Dr Avanish Saxena, Dr Atiharsh Mohan Agarwal, Dr. Sandeep Mangla EFFICACY OF TRANEXAMIC ACID IN REDUCING PERIOPERATIVE BLOOD LOSS DURING CAESAREAN SECTION: A PLACEBO CONTROLLED DOUBLE BLIND STUDY International Journal of Scientific Research, Vol : 5, Issue : 3 March 2016

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