Elevated Inflammation and Neutrophil-Lymphocyte Ratio in Male with Idiopathic Hypogonadotropic Hypogonadism

Havva Keskin; Kenan Cadirci; Yasemin Kaya; Senay Arikan; Ayse Carlioglu

Volume : VIII, Issue : II, February - 2019

Elevated Inflammation and Neutrophil-Lymphocyte Ratio in Male with Idiopathic Hypogonadotropic Hypogonadism

Havva Keskin, Kenan Cadirci, Yasemin Kaya, Senay Arikan, Ayse Carlioglu

Abstract :

Objective: The goal of this study is to determine the NLR in the young male with idiopathic hypogonadotropic hypogonadism (IHH). Methods: A total of 33 isolated and untreated IHH male patients and 56 healthy control males were included in the study. In addition to the blood sampling, anthropometric measures, and physical examination were undertaken to all participants. Results: As inflammatory markers, the NLR and C–reactive protein (CRP) levels were significantly higher in the IHH group than the controls. Also, the uric acid level was higher in the patients group, but it was not statistical significant. This high NLR in the patients with IHH were independent of the fasting glucose, age, and body mass index. Using the cut–off value of NLR>1.46, there was sensitivity at 72.6% and specificity at 73%. Conclusion: In addition to several systemic inflammatory markers, the NLR was higher in males with IHH compared to the healthy ones