Volume : VIII, Issue : III, March - 2019

ELEVATED PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS: A PILOT STUDY

Dr. Swetha Gadde

Abstract :

Plasma homocysteine (Hcy), a novel risk factor for cardiovascular disease, has been found to be increased in inflammatory diseases, such as rheumatoid arthritis(RA). Periodontitis, a chronic inflammatory disease shares a common immunoinflammatory profile with RA. AIM: This study aims to assess the level of plasma Hcy in subjects with chronic periodontitis and to assess the relationship between severity of periodontitis and plasma Hcy levels. Materials and methods: Ten subjects with clinical evidence of chronic periodontitis were selected. Mean probing depth and clinical attachment levels were recorded. Enzyme immune assay was used for the determination of Hcy in plasma. Results: There was no significant association between age,gender with chronic periodontitis, whereas a significant positive correlation was seen with homocysteine levels and mean probing depth. Conclusion: Elevated levels of plasma Hcy were observed in patients with chronic periodontitis and could be marker for systemic inflammation. Further research should be directed on the effect of periodontal therapy and plasma Hcy levels.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

ELEVATED PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS: A PILOT STUDY, Dr. Swetha Gadde INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-3 | March-2019

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