Epidemiology and Treatment of Helicobacter pylori Infection: specific problems in Albania

Ilir Bibolli; Jonida Uku; Eneida Bozaxhiu; Dorina Osmanaj; Bajram Begaj; Skerdi Prifti; Marsela Sina

Volume : IV, Issue : XII, December - 2015

Epidemiology and Treatment of Helicobacter pylori Infection: specific problems in Albania

Ilir Bibolli, Jonida Uku, Eneida Bozaxhiu, Dorina Osmanaj, Bajram Begaj, Skerdi Prifti, Marsela Sina

Abstract :

Helicobacter pylori is a gram negative Campilobacter. It�s one of the most common causes of ulcerous disease. H.pylori causes chronic inflammation, leading to gastric mucose atrophy, even adenocarcinoma or lymphoma. Its presence in the population is highly related to geographic, demographic or genetic characteristics and socio–economic level. Even though ulcerous disease treatment is an evident achievement in the Gastro–enterology service, it still remains a problem because of the microbic resistance, attending for new solutions. In some countries, triple therapy with a proton–pump inhibitor, amoxicillin and clarithromycin is still the best option, but eradication results fall short of what would be desired ( 90–95% ) in countries with clarithromycin resistance >20%, bismuth–containing quadruple therapy, or non–bismuth sequential or concomitant therapies may then be the preferred option. Vaccination would be the best option, especially for developing countries, but little progress has been made in designing a vaccine.