Estimation of anaemic status as the cause behind altered HbA1C level in non diabetic hypothyroid patients

PROF. DR. SOMA GUPTA; SOUMIKA BISWAS

Volume : VI, Issue : III, March - 2017

Estimation of anaemic status as the cause behind altered HbA1C level in non diabetic hypothyroid patients

Prof. Dr. Soma Gupta, Soumika Biswas

Abstract :

Studies across the world have shown that HbA1C is elevated in non–diabetic patients also suffering from hypothyroidism. The falsely elevated HbA1C level in Hypothyroid patients is often explained by anaemia which is a common associated feature . In this study it was investigated whether elevated A1C in non diabetic hypothyroid patients can be due to anaemia. Between March 2016 to September 2016, 63 nondiabetic hypothyroid individuals were tested in the Dept. of Biochemistry ,NRSMC & H for TSH ,fT4,fasting blood glucose,HbA1C & complete haemogram. Non–diabetic hypothyroid individuals with anaemia showed elevated HbA1C levels (5.00 +– 0.35 % ) than those without anaemia (3.59+– 0.27 %), the rise was approx. 1.39 times. Altered erythrocyte life span is partially responsible for this false elevation in HbA1C levels. Hence this conversion factor might be used to correct the haemoglobin status while using HbA1C as a diagnostic tool for diabetes in such patients.